Burden of Hereditary Angioedema: Findings From a US Patient Survey

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Socioeconomic burden of hereditary angioedema: results from the hereditary angioedema burden of illness study in Europe

BACKGROUND Hereditary angioedema (HAE) due to C1 inhibitor deficiency is a rare but serious and potentially life-threatening disease marked by spontaneous, recurrent attacks of swelling. The study objective was to characterize direct and indirect resource utilization associated with HAE from the patient perspective in Europe. METHODS The study was conducted in Spain, Germany, and Denmark to a...

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Comparing acquired angioedema with hereditary angioedema (types I/II): findings from the Icatibant Outcome Survey

Icatibant is used to treat acute hereditary angioedema with C1 inhibitor deficiency types I/II (C1-INH-HAE types I/II) and has shown promise in angioedema due to acquired C1 inhibitor deficiency (C1-INH-AAE). Data from the Icatibant Outcome Survey (IOS) were analysed to evaluate the effectiveness of icatibant in the treatment of patients with C1-INH-AAE and compare disease characteristics with ...

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Burden of Illness in Hereditary Angioedema: A Conceptual Model.

The objective of the Hereditary Angioedema Burden of Illness Study in Europe was to assess the real-world experience of hereditary angioedema (HAE) from the patient perspective. Based on open-ended qualitative interviews with 30 patients from Spain, Germany and Denmark, 5 key themes emerged characterizing the impact of HAE on health-related quality of life (HRQoL): (i) unnecessary treatments an...

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Report on the First Survey of Iranian Patients with Hereditary Angioedema

Background: Hereditary angioedema (HAE) is a rare autosomal dominant primary immunodeficiency with complement system defect characterized by recurrent episodes of angioedema involving the skin or mucosa of the upper respiratory and gastrointestinal tracts. Objective: To characterize the clinical and laboratory data of hereditary angioedema in Iran. Methods: Patients with probable diagnosis of a...

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Perioperative care of a patient with hereditary angioedema

Hereditary angioedema is a rare disorder caused by the congenital deficiency or dysfunction of C1 inhibitor. The deficiency results in recurrent episodes of angioedema, mainly involving the mucosa and skin. The most common clinical manifestations are the result of edema in the subcutaneous tissue, abdominal mucosa, and laryngeal tissue. Laryngeal involvement remains the most serious due to the ...

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ژورنال

عنوان ژورنال: Journal of Allergy and Clinical Immunology

سال: 2018

ISSN: 0091-6749

DOI: 10.1016/j.jaci.2017.12.182