Burden of Haemophilus influenzae type B disease in Pakistani children

نویسندگان
چکیده

منابع مشابه

Burden of Haemophilus influenzae type b disease in Pakistani children.

Estimates of the burden of Haemophilus influenzae type b (Hib) in children in Pakistan are limited. A prospective surveillance was set up in 8 sentinel sites in Karachi and Hyderabad in January 2004. A total of 1481 children aged < 5 years underwent lumbar puncture for suspected acute bacterial meningitis. Specimens from 237 (16.0%) children met the criteria for probable bacterial meningitis, a...

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DETECTION OF HAEMOPHILUS INFLUENZAE TYPE B IN CEREBROSPINAL FLUID OF SUSPECTED CHILDREN WITH MENINGITIS BYPCR

 ABSTRACT Background: A polymerase chain reaction (PCR) assay with primers from "hpd" gene was compared with culture for the detection of Haemophilus influenzae type b (Hib) in CSF samples from children suspected of meningitis. Methods: 300 cerebrospinal fluid (CSF) samples from suspected meningitis cases were studied by culture (Leventhal & Chocolate Agar) and PCR. Results: The latter...

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Haemophilus Influenzae Type B Disease

Before the introduction of effective vaccines, H. influenzae, type b (Hib) was the leading cause of bacterial meningitis and other invasive bacterial disease among children less than 5 years of age. In 1997, ten confirmed cases of invasive disease caused by the serotype b strain of H. influenzae were reported. This is the first year that the number of cases increased since the conjugate vaccine...

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Haemophilus influenzae type b antigenuria in children.

Detection of Haemophilus influenzae type b (HIb) antigenuria by latex agglutination has been shown to be sensitive, specific, and rapid. In children, antigenuria persisted for a mean duration of 10 days and a maximum of 18 days. Antigenuria was demonstrated in 25 of 30 patients with HIb infection but not in 62 with other types of infection. In five children, antigenuria confirmed the diagnosis ...

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Immunogenicity and Efficacy of Different Haemophilus influenzae type b Vaccines

Haemophilus influenzae, a major cause of meningitis in young children leading to death and other neurological sequelae. The disease leaves 15 to 35% of the survivors with permanent disabilities, such as, mental retardation or deafness. Despite the availability of new and more powerful antibiotics children with Hib meningitis still suffer from high mortality or morbidity. The emergence of multir...

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ژورنال

عنوان ژورنال: Eastern Mediterranean Health Journal

سال: 2010

ISSN: 1020-3397,1687-1634

DOI: 10.26719/2010.16.6.590