Buprenorphine for managing opioid withdrawal
نویسندگان
چکیده
منابع مشابه
Managing opioid addiction with buprenorphine.
Legislation has enabled physicians to treat opioid-dependent patients with an office-based maintenance program using buprenorphine, a partial mu-opioid receptor agonist. Clinical studies indicate buprenorphine effectively manages opioid addiction. Buprenorphine is more effective than placebo for managing opioid addiction but may not be superior to methadone if high doses are needed. It is compa...
متن کاملManaging opioid dependence. Comparing buprenorphine with methadone.
analysis comparing the effectiveness of buprenorphine and methadone. Research question Is buprenorphine as effective as methadone for managing opioid dependence? Type of article and design Meta-analysis by three reviewers. Relevance to family physicians Community-based family physicians are uniquely suited to care for opioid-dependent patients. Buprenorphine, like methadone, is a substitution t...
متن کاملBuprenorphine and opioid antagonism, tolerance, and naltrexone-precipitated withdrawal.
The dual antagonist effects of the mixed-action μ-opioid partial agonist/κ-opioid antagonist buprenorphine have not been previously compared in behavioral studies, and it is unknown whether they are comparably modified by chronic exposure. To address this question, the dose-related effects of levorphanol, trans-(-)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl] benzeneacetamide (U50,488...
متن کاملBuprenorphine Withdrawal Syndrome
The increasing use of buprenorphine among drug dependent subjects demands systematic enquiry into the clinical profile of buprenorphine withdrawal. Six male buprenorphine dependent (parenteral) subjects were observed for opiate withdrawal over a two week period. The onset of withdrawal occurred 48 hours after the last dose, peaked around the third day and lasted up to ten days. The withdrawals ...
متن کاملEvaluation of the use of buprenorphine for opioid withdrawal in an emergency department.
OBJECTIVES To examine the use of buprenorphine for the treatment of opioid withdrawal (OW) in an emergency department (ED) setting. METHODS The medical records of all adult patients who presented to the study ED during a 10 week period for OW were abstracted. Subjects were categorized as receiving buprenorphine, symptomatic treatment or no pharmacologic treatment for their OW. The three group...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2017
ISSN: 1465-1858
DOI: 10.1002/14651858.cd002025.pub5