Budd–Chiari syndrome and heparin-induced thrombocytopenia
نویسندگان
چکیده
منابع مشابه
Heparin induced thrombocytopenia
Abstract Background and Objectives Heparin is still a commonly used anticoagulant in prophylaxis and treatment of thromboembolic events. Heparin-induced thrombocytopenia (HIT) is a life-threating adverse drug reaction of heparin. The diagnosis of HIT is made based on two important criteria, firstly clinical evaluation and secondly laboratory testing. In this comprehensive review, the authors w...
متن کاملHeparin-Induced Thrombocytopenia (HIT) Syndrome
Heparin has been available as a clinical treatment and prevention for thromboembolic disease for half a century. Known complications of heparin therapy include bleeding, allergic reactions, osteoporosis, and thrombocytopenia. Heparin-induced thrombocytopenia (HIT) is a common and potentially grave adverse effect of heparin treatment. HIT is unusual among drug-induced thrombocytopenias in that i...
متن کاملHeparin-induced thrombocytopenia.
Heparin-induced thrombocytopenia (HIT) is an immune complication of heparin therapy caused by antibodies to complexes of platelet factor 4 (PF4) and heparin. Pathogenic antibodies to PF4/heparin bind and activate cellular FcγRIIA on platelets and monocytes to propagate a hypercoagulable state culminating in life-threatening thrombosis. It is now recognized that anti-PF4/heparin antibodies devel...
متن کاملHeparin induced thrombocytopenia
Heparin induced thrombocytopenia (HIT) is a prothrombotic syndrome initiated by platelet-activating auto-antibodies with potentially devastating complications. Once the diagnosis of HIT is suspected, discontinuation of heparin and treatment with an alternative anticoagulant are mandatory. While established drugs for HIT are no longer available, parenteral factor Xa inhibitors, thrombin inhibito...
متن کاملHeparin-induced Thrombocytopenia
Nebojša M. Antonijević1, Nebojša Radovanović1, Slobodan Obradović2, Dragica Vučelić6, Bojan Stojanović1, Danijela Miković4, Mirjana Kovač4, Tina Kočica1, Svetlana Tadić4, Irina Antonijević4, Snežana Drašković4, Valentina Djordjević5, Branko Čalija6, Jovan Peruničić1, Zorana Vasiljević1 1 Institute of Cardiovascular Diseases, Clinical Centre of Serbia, Belgrade, Serbia; 2 Clinic of Emergency Med...
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ژورنال
عنوان ژورنال: European Journal of Cardio-Thoracic Surgery
سال: 2001
ISSN: 1873-734X,1010-7940
DOI: 10.1016/s1010-7940(01)00625-x