BRS1 mediates plant redox regulation and cold responses

Abstract Background Brassinosteroid-insensitive 1 suppressor (BRS1) is a serine carboxypeptidase that mediates brassinosteroid signaling and participates in multiple developmental processes Arabidopsis. However, little known about the precise role of BRS1 this context. Results In study, we analyzed transcriptional proteomic profiles Arabidopsis seedlings overexpressing found gene was involved both cold stress responses redox regulation. Further evidence showed regulated cell by indirectly interacting with cytosolic NADP + -dependent isocitrate dehydrogenase (cICDH). One novel alternative splice form identified over-expression mutants brs1-1D, which may confer new plant development responses. Conclusions This study highlights regulation responses, extends our understanding extracellular carboxypeptidases.