منابع مشابه
Detection of sulfur dioxide in bronchodilator aerosols.
Several bronchodilator drugs commonly used in respiratory therapy contain sodium metabisulfite as an antioxidant preservative. When aerosolized, these agents may release the irritant gas SO2 as a result of bisulfite decomposition. We found that agents that contain bisulfites generated SO2 concentrations of 2.0 ppm and greater, while bronchodilator solutions without bisulfite did not. Such level...
متن کاملEffects of bronchodilator particle size in asthmatic patients using monodisperse aerosols.
Aerosol particle size influences airway drug deposition. Current inhaler devices are inefficient, delivering a heterodisperse distribution of drug particle sizes where, at best, 20% reaches the lungs. Monodisperse aerosols are the appropriate research tools to investigate basic aerosol science concepts within the human airways. We hypothesized that engineering such aerosols of albuterol would i...
متن کاملComparative study of duration of action and cardiovascular effects of bronchodilator aerosols.
The durations of action and side effects of four different pressurized bronchodilator aerosols were compared. One of the preparations contained isoprenaline alone, which was given in a dose of 400 /tg. The doses of the three other preparations were adjusted to yield nearly the same peak bronchodilator response as was obtained from 400 jtg isoprenaline. These doses differed from those yielded by...
متن کاملEffect of particle size of bronchodilator aerosols on lung distribution and pulmonary function in patients with chronic asthma.
The particle size of bronchodilator aerosols may be important in determining the site of deposition in the lung and their therapeutic effect. The distribution of aerosols (labelled with technetium-99m diethylene triamine pentacetic acid) of two different particle sizes has been studied by gamma camera imaging. The particles had mass median aerodynamic diameters (geometric standard deviations) o...
متن کاملBronchodilator reversibility to albuterol predicts bronchodilator response to salmeterol.
We read with interest the recent study by Fish et al (August 2001)1 showing that adding salmeterol to inhaled corticosteroid achieved superior control as compared to adding montelukast. However it is likely that the results were biased toward the long-acting 2-agonist as patients were required as an inclusion criteria to have at least 12% increase in FEV1 in response to albuterol. It is therefo...
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ژورنال
عنوان ژورنال: BMJ
سال: 1969
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.4.5682.557