Bronchoalveolar Lavage (BAL) for Research; Obtaining Adequate Sample Yield
نویسندگان
چکیده
منابع مشابه
Bronchoalveolar Lavage (BAL) for Research; Obtaining Adequate Sample Yield
We describe a research technique for fiberoptic bronchoscopy with bronchoalveolar lavage (BAL) using manual hand held suction in order to remove nonadherent cells and lung lining fluid from the mucosal surface. In research environments, BAL allows sampling of innate (lung macrophage), cellular (B- and T- cells), and humoral (immunoglobulin) responses within the lung. BAL is internationally acce...
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BACKGROUND Sarcoidosis is a chronic granulomatous lung disease of unknown origin. The accumulation of activated T cells at sites of inflammation represents an early stage in granuloma formation. Since mechanisms governing the normal resolution of inflammatory processes are poorly understood, this study aimed to investigate the apoptotic phenotype of peripheral blood and lung T lymphocytes from ...
متن کاملBronchoalveolar lavage--obtaining biologic specimens from the respiratory tract surface.
Dating to fifth century BCE in Greece and the Hippocratic Movement of Physicians that created the beginnings of Western Medicine, a combination of bodily fluids and discharges, termed humors, described how the human body functioned. Among the four humors, phlegm was one and was connected to old age and winter (1). Consider that respiratory secretions in the elderly might reflect the cumulative ...
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The importance of predefined criteria for acceptable samples of respiratory therapists obtained lower respiratory samples were studied, using a nonbronchoscopic bronchoalveolar lavage (BAL) protocol for ventilated patients in the intensive care unit. Therapists were instructed and asked to follow guidelines for obtaining samples. Over one year, 219 samples were obtained by respiratory therapist...
متن کاملBronchoalveolar lavage as a research tool.
Researchers over the past 40 years have utilized bronchoalveolar lavage (BAL) as a tool to help expand our knowledge of pulmonary medicine. Many reports have documented BAL as a safe procedure for research subjects. New technologies, such as flow cytometry, have provided much needed insight into the mechanisms behind several pulmonary diseases. The concept of the lung as an easily accessible mu...
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ژورنال
عنوان ژورنال: Journal of Visualized Experiments
سال: 2014
ISSN: 1940-087X
DOI: 10.3791/4345