منابع مشابه
Breathing pattern during bronchial challenge in humans.
Increases in minute ventilation (V'E) have been observed during exacerbations of asthma and in response to administration of histamine. However, it is not yet clear how the breathing pattern is affected, and whether the increase in V'E is found in general. In the present study, the effects of inhalation of histamine on respiratory frequency (fR), tidal volume (VT), V'E, and on functional residu...
متن کاملMethacholine bronchial challenge using a dosimeter with controlled tidal breathing.
A new inhalation synchronised dosimeter triggered by low inspiratory flow rates has been assessed. The methacholine challenge test using dosimeter nebulisation with controlled tidal breathing was compared with continuous nebulisation using De Vilbiss No 40 nebulisers with deep inhalations in 11 asthmatic subjects. Within subject PD20 FEV1 values were lower with the dosimeter method than with th...
متن کاملRespiratory and haemodynamic response to carbon dioxide breathing in patients with and without bronchial obstruction.
1. The effect of breathing a mixture of 5-6% carbon dioxide in air was examined in seven patients with obstructive bronchitis and in eight patients with lung disease but without bronchial obstruction. 2. Hyperventilation during CO2 breathing was less marked in patients with bronchial obstruction than in the others. Cardiac output did not change in patients with airways obstruction but rose in t...
متن کاملEffect of bronchial challenge on breathing patterns and arterial oxygenation in stable asthma.
The effect of histamine or methacholine inhalational challenge on breathing patterns and oxygen saturation was investigated in ten stable asthmatic patients. We used the respiratory inductive plethysmograph to record respiratory timing and minute ventilation along with an ear oximeter to measure oxygen saturation (SaO2). As FEV1 fell during the challenge procedure, SaO2 also fell (average 3 per...
متن کاملBronchial provocation in the study of sensations associated with disordered breathing.
1. Lung volumes, airway resistance and flow/volume curves were measured in ten asthmatic subjects at times when tightness in the chest was just sensed (threshold symptom). 2. These measurements when the threshold symptom was induced by methacholine inhalation were compared with those when a similar symptom occurred spontaneously, in the same subjects. 3. Values during the methacholine-induced t...
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ژورنال
عنوان ژورنال: BMJ
سال: 1897
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.1924.1418-a