BRMS1L mediated effect of miR-20a-5p expression on proliferation and apoptosis of gastric cancer cells

Cancer causes most fatalities worldwide next only to cardiovascular disease. Early diagnosis helps reduce such incidences. In gastric cancer, abnormal expressions of micro ribonucleic acids (miRNAs) could serve as a marker. However, studies involving both miR-20a-5p and BRMS1L are limited. Here, we studied the acid (miR)-20a-5p its target gene breast cancer metastasis suppressor 1-like (BRMS1L) in tissues their effects on proliferation apoptosis cells. The expression was significantly higher lower than those paracancerous (P <0.05). correlated with tumor-node-metastasis stage, lymph node metastasis, infiltration depth differentiation degree group had raised cell ability cyclin D1 Bcl-2 well reduced caspase-3 protein control miR-NC groups MiR-20a-5p is highly expressed cells, overexpression can facilitate suppress