منابع مشابه
British motor neuron disease twin study.
OBJECTIVES To investigate the cause of sporadic motor neuron disease (MND) by twin study, so allowing (1) estimation of the genetic contribution, and (2) collection of matched pairs for a case-control study of possible environmental factors. METHODS 10872 death certificates bearing the diagnosis MND were collected from 1979 to 1989 inclusive. Inspection of individual birth entries allowed ide...
متن کاملMotor Neuron Disease
Neurologists in the 19th century recognized that muscle weakness could be due to primary disorders of muscle or secondary to loss of neuromuscular integrity, as happens when peripheral nerves are cut or when motor neurons degenerate. Furthermore, it was observed that there are forms of motor neuron degeneration which selectively affect upper motor neurons or lower motor neurons. A combination o...
متن کاملAssessing motor neuron disease.
Hadjikoutis and Wiles draw attention to a number of circumstances in which the serum chloride and bicarbonate can be misleading. They do not mention that they will also be misleading if they are measured when hypercapnia is increasing or decreasing. An exacerbation of hypercapnia will take 4 – 6 days to raise the serum bicarbonate and lower the serum chloride to new steady levels. 1 How long it...
متن کاملMotor neuron disease
Motor neuron disease (MND) represents one ofthe major unsolved problems in neurology. The literature is characterized by numerous speculative theories, mostly derived by analogy with other recognized causes of motor neuron death such as poliomyelitis, or from toxic exposures such as lead poisoning. However, analogous reasoning of this type has not, so far, given insights into MND itself, or res...
متن کاملPain in motor neuron disease.
Twenty-seven of 42 patients with motor neuron disease had significant pain. The nature and duration of the pain are described along with an illustrative case-report. The aetiology and most effective treatment of this common complication of motor neuron disease remain unclear.
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 1997
ISSN: 0022-3050
DOI: 10.1136/jnnp.62.6.562