منابع مشابه
Breaking Up Just Got Easier to Do
The SLX4 protein functions as a platform for catalytic subunits of structure-specific endonucleases. Findings reported in Cell (Fekairi et al., 2009; Svendsen et al., 2009) and in Molecular Cell (Andersen et al., 2009; Muñoz et al., 2009) now identify the human SLX4 and show that in association with the SLX1 endonuclease it directs the symmetric cleavage and resolution of Holliday junctions.
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In preparation for meiosis, chromosomes go through several massive structural transitions, including chromosome fragmentation, pairing and synapsis. A checkpoint factor and a SUMO ligase collaborate to keep things in order.
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Our understanding of the early steps in the evolution of life is hampered by a Catch-22: Darwinian selection leading to longer genomes requires as prerequisite increased replicative fidelity. Yet a genome at capacity cannot increase in size; it will be catastrophically mutated out of existence if fidelity has not already increased. Traditionally the problem has been considered for genotypes but...
متن کاملBreaking up Isn't Hard to Do
lent work. Everyone with anything to do with Dictyoste-Wackett and Hershberger have summarized over 90 functional groups in organic molecules, ranging from lium should read this. Scientists who are wondering simple alcohols to tricycloaliphatic rings. Microbes are whether or not to dip their toes will get a better idea of known to have strategies for dealing with 58 of these. whether social amo...
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ژورنال
عنوان ژورنال: Cell
سال: 2009
ISSN: 0092-8674
DOI: 10.1016/j.cell.2009.06.039