Branching-type microtubule nucleation in higher plants
نویسندگان
چکیده
منابع مشابه
Neuronal Morphogenesis: Golgi Outposts, Acentrosomal Microtubule Nucleation, and Dendritic Branching
In large cells like neurons, how is microtubule polymerization initiated at large distances from the cell body and the main microtubule-organizing center? In this issue of Neuron, Ori-McKenney et al. (2012) demonstrate that Golgi outposts mediate acentrosomal microtubule nucleation and reveal it is crucial for dendrite morphogenesis.
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The microtubules that comprise mitotic spindles in animal cells are nucleated at centrosomes and by spindle assembly factors that are activated in the vicinity of chromatin. Indirect evidence has suggested that microtubules also might be nucleated from pre-existing microtubules throughout the spindle, but this process has not been observed directly. Here, we demonstrate microtubule nucleation f...
متن کاملStructural analysis of the role of TPX2 in branching microtubule nucleation
The mitotic spindle consists of microtubules (MTs), which are nucleated by the γ-tubulin ring complex (γ-TuRC). How the γ-TuRC gets activated at the right time and location remains elusive. Recently, it was uncovered that MTs nucleate from preexisting MTs within the mitotic spindle, which requires the protein TPX2, but the mechanism basis for TPX2 action is unknown. Here, we investigate the rol...
متن کاملCOMMENTARY Centrosome-microtubule nucleation
In many cell types the formation of microtubules from tubulin subunits is initiated at defined nucleation sites at the centrosome. These sites contain the conserved γ-tubulin which is in association with additional not very well characterised proteins, identified as components of a γ-tubulin ring complex from Xenopus egg extracts or from suppressor screens in the yeast Saccharomyces cerevisiae....
متن کاملAugmin-dependent microtubule nucleation at microtubule walls in the spindle
The formation of a functional spindle requires microtubule (MT) nucleation from within the spindle, which depends on augmin. How augmin contributes to MT formation and organization is not known because augmin-dependent MTs have never been specifically visualized. In this paper, we identify augmin-dependent MTs and their connections to other MTs by electron tomography and 3D modeling. In metapha...
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ژورنال
عنوان ژورنال: PLANT MORPHOLOGY
سال: 2006
ISSN: 1884-4154,0918-9726
DOI: 10.5685/plmorphol.18.47