Brain Atrophy in Clinically Isolated Syndrome
نویسندگان
چکیده
منابع مشابه
Corpus Callosum Atrophy and Diffusion Abnormalities in Clinically Isolated Syndrome Revealed by Diffusion Tensor Tractography
Introduction Many previous studies have observed atrophy and abnormal water diffusivity within the corpus callosum (CC) of multiple sclerosis (MS) patients [1, 2]. However, few studies have addressed the question whether such abnormalities exist in the earlier stages of MS, especially in clinically isolated syndrome (CIS). In this study, we aimed to investigate CC abnormalities in CIS patients ...
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One of the fundamental tasks in the inflammatory arena is to prevent the conversion of a Whilst there are many theories, over many years, the exact cause of multiple sclerosis (MS) is unknown. Despite having to peer through this mist, unparalled advances have been made over the last 2 decades with transformative treatments, usually with an anti-inflammatory basis. Yet if treatment could begin a...
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BACKGROUND Axonal damage is considered a major cause of disability in multiple sclerosis (MS) and may start early in the disease. Specific biomarkers for this process are of great interest. OBJECTIVE To study if cerebrospinal fluid (CSF) biomarkers for axonal damage reflect and predict disease progression already in the earliest stages of the disease, that is, in clinically isolated syndrome ...
متن کاملAsperger syndrome, violent thoughts and clinically isolated syndrome.
A young man, 23 years old, with a clinically isolated syndrome (CIS), presented violent thoughts during a neurological consultation. He was diagnosed with Asperger Syndrome based on a psychiatric and (neuro)psychological examination. Possible risk factors for acting-out and the implications for treatment, if CIS would evolve to MS, are discussed based on a review of the literature.
متن کاملDisrupted topological organization of structural and functional brain connectomes in clinically isolated syndrome and multiple sclerosis
The brain connectome of multiple sclerosis (MS) has been investigated by several previous studies; however, it is still unknown how the network changes in clinically isolated syndrome (CIS), the earliest stage of MS, and how network alterations on a functional level relate to the structural level in MS disease. Here, we investigated the topological alterations of both the structural and functio...
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ژورنال
عنوان ژورنال: Neurología (English Edition)
سال: 2010
ISSN: 2173-5808
DOI: 10.1016/s2173-5808(10)70080-8