<b>Pharmacokinetics of Darbepoetin Alfa after Single Intravenous Injection of 5 μg in Patients on Hemodialysis</b>
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چکیده
منابع مشابه
Pharmacokinetics of tetracycline hydrochloride after single intravenous injection in dogs
Six mixed-breed apparently healthy dogs were intravenously administered a single dose of tetracycline hydrochloride (50 mg/kg) to evaluate the pharmacokinetic parameters of the drug. Blood samples were collected before and at various time intervals after the administration of the drug. Serum tetracycline concentrations were determined over a 24 h period using fluorescence spectrophotometry. Non...
متن کاملClinical Trial Simulation of a 200-μg Fixed Dose of Darbepoetin Alfa in Chemotherapy-Induced Anemia
nemia is a common complication in patients with cancer.[1,2] Anemia, defined by low hemoglobin or a low red blood cell (RBC) count, can be a consequence of the myelotoxicity of the chemotherapy regimen (especially platinum-containing regimens) or an inherent effect of the cancer itself (particularly in multiple myeloma, lymphomas, or metastatic bone disease). Although approximately 50% of patie...
متن کاملPharmacology of darbepoetin alfa.
The distinct molecular structure of darbepoetin alfa, in both its amino acid sequence and its carbohydrate content, results in a biologic profile with lower binding affinity, longer circulating half-life, and higher in vivo potency compared with the epoetins. The mechanisms responsible for these differences in biological effects have not been fully explained. Pharmacokinetic investigations of d...
متن کاملpharmacokinetics of tetracycline hydrochloride after single intravenous injection in dogs
six mixed-breed apparently healthy dogs were intravenously administered a single dose of tetracycline hydrochloride (50 mg/kg) to evaluate the pharmacokinetic parameters of the drug. blood samples were collected before and at various time intervals after the administration of the drug. serum tetracycline concentrations were determined over a 24 h period using fluorescence spectrophotometry. non...
متن کاملon translation of politeness strategies in dialogues involving female characters in translations and retranslations of novels translated before and after the islamic revolution of iran and their effects on the image of women: a polysystem theory approach
abstract reception environment has considerable effects on accepting a translation. as the expectations of a target culture and its values and needs change throughout history, its criteria for accepting a translation or rejecting it will change accordingly (gentzler, 2001). the expectations of iran, as the reception environment in the present study, have changed after the islamic revolution. i...
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ژورنال
عنوان ژورنال: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics
سال: 2015
ISSN: 0388-1601,1882-8272
DOI: 10.3999/jscpt.46.253