Bovine Somatotropin Attenuates Phorbol Ester-Induced Prostaglandin F2 Production in Bovine Endometrial Cells
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چکیده
منابع مشابه
Differential effects of interferon-tau on the prostaglandin synthetic pathway in bovine endometrial cells treated with phorbol ester.
Rationale for these experiments was to evaluate the dose effects of bovine interferon-tau (IFN-tau) on the prostaglandin secretory pathway of immortalized bovine endometrial (BEND) cells in response to phorbol 12, 13-dibutyrate (PdBu) and to characterize similar responses in primary bovine uterine epithelial cells as a biomonitor of embryo-induced antiluteolytic effects on the endometrium. The ...
متن کاملPhospholipase A2 regulation of bovine endometrial (BEND) cell prostaglandin production
BACKGROUND Prostaglandins (PG), produced by the uterine endometrium, are key regulators of several reproductive events, including estrous cyclicity, implantation, pregnancy maintenance and parturition. Phospholipase A2 (PLA2) catalyzes the release of arachidonic acid from membrane phospholipids, the rate-limiting step in PG biosynthesis. The bovine endometrial (BEND) cell line has served as a m...
متن کاملDistinct phospholipase A2 enzymes regulate prostaglandin E2 and F2alpha production by bovine endometrial epithelial cells
BACKGROUND The rate-limiting step in prostaglandin (PG) biosynthesis is catalyzed by phospholipase A2 (PLA2) enzymes which hydrolyze arachidonic acid from membrane phospholipids. Despite their importance in uterine PG production, little is known concerning the specific PLA2 enzymes that regulate arachidonic acid liberation in the uterine endometrium. The objectives of this study were to evaluat...
متن کاملPolyunsaturated Fatty Acids and Bovine Interferon-t Modify Phorbol Ester-Induced Secretion of Prostaglandin F2a and Expression of Prostaglandin Endoperoxide Synthase-2 and Phospholipase-A2 in Bovine Endometrial Cells1
Embryonic mortality in cattle may occur because of inadequate inhibition of uterine secretion of prostaglandin (PG) F2a mediated by bovine interferon-t (bIFN-t). The objectives of the present study were to determine whether polyunsaturated fatty acids inhibit secretion of PGF2a from bovine endometrial cells induced by stimulating protein kinase C with phorbol 12,13 dibutyrate (PDBu) and to inve...
متن کاملProduction of polyclonal antibodies directed to recombinant methionyl bovine somatotropin.
The administration of recombinant methionyl bovine somatotropin (rMbST) to dairy cows to increase milk yield remains a common practice in many countries including the USA, Brazil, Mexico, South Africa and Korea, whereas it has been forbidden within the European Union (EU) since 1999. A rapid screening immunoanalytical method capable of the unequivocal determination of rMbST in milk would be hig...
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ژورنال
عنوان ژورنال: Journal of Dairy Science
سال: 2002
ISSN: 0022-0302
DOI: 10.3168/jds.s0022-0302(02)74106-4