Botulinum toxin type A (incobotulinumtoxinA) in cerebral palsy: Combined treatment of spasticity and sialorrhea
نویسندگان
چکیده
منابع مشابه
The Effect of Foot Serial Casting Along with Botulinum Toxin Type-A Injection on Spasticity in Children with Cerebral Palsy
Background & Aims: The goal of this study was to determine the effect of foot serial casting along with botulinum toxin type-A injection on spasticity in children with cerebral palsy. Methods: This study was a randomized clinical trial performed as a pre-post, double blind study. It was performed on 25 children with hemiplegia and diplegia (2-8 years) in Tehran city, who were referred to valias...
متن کاملBotulinum Toxin Treatment for Limb Spasticity in Childhood Cerebral Palsy
CP is the most common cause of chronic disability in childhood occurring in 2-2.5/1000 births. It is a severe disorder and a significant number of patients present cognitive delay and difficulty in walking. The use of botulinum toxin (BTX) has become a popular treatment for CP especially for spastic and dystonic muscles while avoiding deformity and pain. Moreover, the combination of physiothera...
متن کاملBotulinum toxin type A in the treatment of lower limb spasticity in cerebral palsy.
OBJECTIVES To determine whether botulinum toxin (BtA) is an effective and safe treatment for lower limb spasticity in children with cerebral palsy. Functional outcomes are of particular interest. SEARCH STRATEGY Studies for inclusion in the review were identified using the Movement Disorders Review Group trials register, the Cochrane Controlled Trials Register, MEDLINE, pharmaceutical company...
متن کاملBotulinum toxin type A in the treatment of lower-limb spasticity in children with cerebral palsy.
We evaluated the safety and effectiveness of botulinum toxin A (BoNT/A) in the treatment of spasticity in 20 children with spastic diplegic cerebral palsy (CP). All the patients received injections in the gastrocnemius and soleus, and 15 received injections in the adductors. The total dose varied from 70 to 140 U (99.75+/-16.26 U), or 7.45+/-2.06 U/kg per patient. The treatment improved the pat...
متن کاملBotulinum Toxin A in the Treatment of Sialorrhea in Children with Cerebral Palsy
INTRODUCTION Sialorrhea is problematic for many neurologically impaired patients. They suffer from excessive salivation because of inadequate oral motor control or swallowing dysfunction [1]. Persistent sialorrhea creates major hygienic and psychosocial problems. Maceration of skin around the mouth and neck may result in secondary bacterial infection. In addition, drooling is not a respectable ...
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ژورنال
عنوان ژورنال: Toxicon
سال: 2021
ISSN: 0041-0101
DOI: 10.1016/j.toxicon.2020.11.432