Botulinum Toxin A to sialorrhea treatment: a systematic review

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Botulinum toxin A in the treatment of sialorrhea.

OBJECTIVE To review the efficacy and safety of botulinum toxin A (BTX) in the treatment of sialorrhea. DATA SOURCES A PubMed search and reference list review was performed to find clinical trials on BTX in the treatment of sialorrhea. The search was limited to English-language trials involving human subjects. Articles from 1965 to October 2006 were searched, using key words botulinum, botulin...

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Application of botulinum toxin to treat sialorrhea in amyotrophic lateral sclerosis patients: a literature review

Amyotrophic lateral sclerosis is a progressive and fatal neurodegenerative disease characterized by the degeneration of motor neurons, which are the central nervous system cells that control voluntary muscle movements. The excessive salivation (sialorrhea) is present in approximately 50% of amyotrophic lateral sclerosis cases. Thus, some alternative therapeutic methods are sought, such as antic...

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Treatment of severe axillary Hyperhidrosis with Botulinum toxin A

Background: Severe axillary hyperhidrosis causes considerable emotional stress to individuals affected with this condition. Existing topical and surgical therapies are either ineffective or associated with unacceptable morbidity and sequelae. Objective: In this study we attempted to determine the effect of botulinum toxin A (Dysport) in the treatment of axillary hyperhidrosis. Patients and Meth...

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Botulinum toxin type A treatment for Parkinsonian patients with moderate to severe sialorrhea.

PURPOSE To investigate the effect of botulinum toxin type A (BTX-A; Botox) in reducing saliva in patients with Parkinsonism. METHODS Fifteen patients with clinical diagnosis of idiopathic Parkinson's disease, dementia with Lewy bodies, or multiple system atrophy were enrolled in this open clinical trial. A total of 40-unit dose of Botox was injected into the bilateral parotid and submandibula...

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Botulinum Toxin A in the Treatment of Sialorrhea in Children with Cerebral Palsy

INTRODUCTION Sialorrhea is problematic for many neurologically impaired patients. They suffer from excessive salivation because of inadequate oral motor control or swallowing dysfunction [1]. Persistent sialorrhea creates major hygienic and psychosocial problems. Maceration of skin around the mouth and neck may result in secondary bacterial infection. In addition, drooling is not a respectable ...

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ژورنال

عنوان ژورنال: Acta Fisiátrica

سال: 2013

ISSN: 0104-7795

DOI: 10.5935/0104-7795.20130024