Boosting nanotoxicity to combat multidrug-resistant bacteria in pathophysiological environments
نویسندگان
چکیده
منابع مشابه
A traceless reversible polymeric colistin prodrug to combat multidrug-resistant (MDR) gram-negative bacteria.
Colistin methanesulfonate (CMS) is the only prodrug of colistin available for clinical use for the treatment of infections caused by multidrug-resistant (MDR) Gram-negative bacteria. Owing to its slow and variable release, an alternative is urgently required to improve effectiveness. Herein we describe a PEGylated colistin prodrug whereby the PEG is attached via a cleavable linker (col-aaPEG) i...
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To the Editor: In many parts of the world, the proportions of methicil-lin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant en-terococci, and extended-spectrum β-lactamase (ESBL)–producing organisms in the family Enterobacteriaceae have increased remarkably during recent years (1). However, proportions of antimicrobial drug resistance vary substantially at national and regional leve...
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ژورنال
عنوان ژورنال: Nanoscale Advances
سال: 2020
ISSN: 2516-0230
DOI: 10.1039/d0na00644k