Bonus? no, just an onus

Bonus? No, just an onus.

Ray Kurzweil and Uploading: Just Say No!

There is a debate about the possibility of mind-uploading – a process that purportedly transfers human minds and therefore human identities into computers. This paper bypasses the debate about the metaphysics of mind-uploading to address the rationality of submitting yourself to it. I argue that an ineliminable risk that mind-uploading will fail makes it prudentially irrational for humans to un...

Runx1: no longer just for leukemia.

Some 20 years after original work positioned Runx1 as crucial for haematopoiesis and leukaemia formation (Miyoshi et al, 1991; Okuda et al, 1996), a study in this issue of the EMBO Journal (Scheitz et al, 2012) reveals that the RUNX1/Stat3 axis also promotes carcinogenesis in epithelial tissues. RUNX1, the DNA-binding subunit of heterodimeric transcription factor CBF, was first identified as a ...

Refractive Surgery Bonus Feature

SEPTEMBER 2010 CATARACT & REFRACTIVE SURGERY TODAY EUROPE 25 A stigmatism is an optical defect that may lead to shadowing, loss of contrast sensitivity, distortion, blurred vision, and ghosting. There are two types of astigmatism, regular and irregular. Irregular astigmatism is often caused by a corneal scar or scattering in the crystalline lens. It is estimated that astigmatism of more than -0...

Cataract Surgery Bonus Feature

JULY/AUGUST 2010 CATARACT & REFRACTIVE SURGERY TODAY EUROPE 15 H ydrophilic IOLs have many appealing characteristics, such as good optical clarity, good biocompatibility, a low incidence of dysphotopias, and good compressibility allowing implantation through small incisions. Many of these characteristics are due to the water content of hydrophilic lenses, which can vary from 18% to 30%. In cont...