Bone pathologic fracture revealing an unusual association: coexistence of Langerhans cell histiocytosis with Rosai-Dorfman disease
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Bone pathologic fracture revealing an unusual association: coexistence of Langerhans cell histiocytosis with Rosai-Dorfman disease
BACKGROUND The coexistence of Rosai-Dorfman disease (RDD) with Langerhans cell histiocytosis (LCH) is very rare, as to date only 17 cases have been reported in the english literature. The pathophysiology of this uncommon co-occurrence still remains enigmatic and a subject of various speculations. CASE PRESENTATION We report a case of a 30-year-old female patient who presented with a pathologi...
متن کاملAuthor’s response to reviews Title: Bone pathologic fracture revealing an unusual association : Coexistence of Langerhans cell histiocytosis with Rosai-Dorfman disease Case report and a literature review Authors:
Title: Bone pathologic fracture revealing an unusual association : Coexistence of Langerhans cell histiocytosis with Rosai-Dorfman disease Case report and a literature review Authors: Boubacar Efared ([email protected]) Asmae Mazti ([email protected]) Badarou Chaibou ([email protected]) Gabrielle Atsame-Ebang ([email protected]) Ibrahim Sory Sidibé ([email protected]...
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Rosai-Dorfman disease (RDD) is a reactive multisystem histiocytosis that typically presents with cervical lymphadenopathy and systemic symptoms. Cutaneous involvement occurs in approximately 10% of cases, and 3% of cases are limited to the skin without nodal or other extranodal involvement. Langerhans cell histiocytosis (LCH) is a clonal histiocytosis with a wide spectrum of presentations rangi...
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A 7-year-old West African male patient presented with recurrence of multiple cervical lymphadenopathy. Cervical node biopsy disclosed a sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman-Destombes disease). During follow-up, the patient developed a left orbital mass corresponding to an enlarged lacrimal gland shown by CT. The histologic features of the gland were consistent with th...
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ژورنال
عنوان ژورنال: BMC Clinical Pathology
سال: 2017
ISSN: 1472-6890
DOI: 10.1186/s12907-017-0044-1