منابع مشابه
Bone morphogenetic protein guts it out
Hippo throws its weight behind migrating cells L ucas et al. show that the Hippo pathway helps polarize actin so that groups of Drosophila cells can move in unison. Cells often journey in packs during development and cancer metastasis. In the Drosophila ovary, a group of 4–8 border cells traverses the egg chamber and sidles up to the maturing egg. This maneuver requires adjustments by the actin...
متن کاملThe Classic: Bone Morphogenetic Protein
This Classic Article is a reprint of the original work by Marshall R. Urist and Basil S. Strates, Bone Morphogenetic Protein. An accompanying biographical sketch of Marshall R. Urist, MD is available at DOI 10.1007/s11999-009-1067-4; a second Classic Article is available at DOI 10.1007/s11999-009-1069-2; and a third Classic Article is available at DOI 10.1007/s11999-009-1070-9. The Classic Arti...
متن کاملBone Morphogenetic Protein-4 and Bone Morphogenetic Protein Receptors Expressions in the Adult Rat Eye
We investigated the expressions of bone morphogenetic protein-4 (BMP4) and its receptors, bone morphogenetic protein receptor IA (BMPRIA), bone morphogenetic protein receptor IB (BMPRIB) and bone morphogenetic protein receptor II (BMPRII) in the adult rat eye. Interesting differences in expression profile were observed between BMPRIA and BMPRIB in the retina. BMPRIA-like immunoreactivity (IR) w...
متن کاملTrkC binds to the bone morphogenetic protein type II receptor to suppress bone morphogenetic protein signaling.
TrkC, a member of the tropomyosin-related kinase (Trk) family of neurotrophin receptors, is implicated in the growth and survival of human cancer tissues. TrkC is also a potent oncoprotein expressed in tumors derived from multiple cell lineages, and functions as an active protein tyrosine kinase by neurotrophin-3 (NT-3). We previously reported that TrkC plays an essential role in tumor growth a...
متن کاملThe guts of it.
Society and the English language afford 'guts' almost independent sentient being status. Long considered the source of courage, 'that took guts'; determination, 'what a gutsy effort'; and instinct or intuition, 'I had a gut feeling', the guts have also been an emotional powerhouse - disappointment is likened to 'being kicked in the guts' and an intense dislike for someone can be summed up by 'I...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2013
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.2016iti3