Bone health in children and adolescents with perinatal HIV infection

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Bone health in children and adolescents with perinatal HIV infection

The long-term impact on bone health of lifelong HIV infection and prolonged ART in growing and developing children is not yet known. Measures of bone health in youth must be interpreted in the context of expected developmental and physiologic changes in bone mass, size, density and strength that occur from fetal through adult life. Low bone mineral density (BMD) appears to be common in perinata...

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Executive Functioning in Children and Adolescents With Perinatal HIV Infection.

BACKGROUND Perinatal HIV (PHIV) infection may place youth at risk for impairments in executive functioning (EF). We examined associations of EF with HIV infection, disease severity and other factors among youth with PHIV and perinatally HIV-exposed, uninfected youth (PHEU). METHODS Within the US-based Pediatric HIV/AIDS Cohort Study, 354 PHIV and 200 PHEU youth completed a standardized EF mea...

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Bone mineral density in children and adolescents with perinatal HIV infection.

OBJECTIVE To estimate prevalence of low bone mineral density (BMD) in perinatally HIV-infected (HIV+) and HIV-exposed but uninfected (HEU) children, and to determine predictors of BMD in HIV+. DESIGN Cross-sectional analysis within a 15-site United States and Puerto Rico cohort study. METHODS Total body and lumbar spine BMD were measured using dual energy-X-ray absorptiometry. BMD Z-scores ...

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Kidney disease in children and adolescents with perinatal HIV-1 infection

INTRODUCTION Involvement of the kidney in children and adolescents with perinatal (HIV-1) infection can occur at any stage during the child's life with diverse diagnoses, ranging from acute kidney injury, childhood urinary tract infections (UTIs), electrolyte imbalances and drug-induced nephrotoxicity, to diseases of the glomerulus. The latter include various immune-mediated chronic kidney dise...

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The challenges of success: adolescents with perinatal HIV infection

The great success in the prevention and treatment of pediatric HIV in high resource countries, and now in low resource countries, has changed the face of the HIV epidemic in children from one of near certain mortality to that of a chronic disease. However, these successes pose new challenges as perinatally HIV-infected youth survive into adulthood. Increased survival of HIV-infected children is...

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ژورنال

عنوان ژورنال: Journal of the International AIDS Society

سال: 2013

ISSN: 1758-2652

DOI: 10.7448/ias.16.1.18575