Bone disease in pediatric idiopathic hypercalciuria
نویسندگان
چکیده
منابع مشابه
Bone disease and idiopathic hypercalciuria.
Observational and epidemiologic studies alike have shown that idiopathic hypercalciuric (IH) stone-forming patients typically show bone mineral density scores that are significantly lower than those observed for age- and sex-matched normal subjects or those for nonhypercalciuric stone-forming patients. Most of these studies have relied on changes in bone mineral density and have not explored th...
متن کاملClinical manifestations of pediatric idiopathic hypercalciuria.
Idiopathic hypercalciuria (IH) is a common metabolic disorder in children with protean manifestations, many of which can mimic other common pediatric diseases. Reports in the medical literature describe children with IH presenting with a wide array of calculi and non-calculi related clinical symptoms such as hematuria, urinary tract infections (UTIs), urgency, urinary incontinence and recurrent...
متن کاملTreatment strategies for pediatric idiopathic hypercalciuria.
Idiopathic hypercalciuria (IH) is a common metabolic disorder in children and is associated with the development of renal calculi, nephrocalcinosis, hematuria and osteopenia. The effect of various dietary modifications and available pharmacologic therapies on reducing urinary calcium excretion and/or urinary supersaturation is discussed in this article. The importance of a multidisciplinary app...
متن کاملRANKL is a mediator of bone resorption in idiopathic hypercalciuria.
BACKGROUND AND OBJECTIVES This study aimed to determine the expression of osteoprotegerin, receptor activator of nuclear factor kappaB ligand, interleukin-1alpha, transforming growth factor-beta, and basic fibroblast growth factor in stone-forming patients with idiopathic hypercalciuria. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Immunohistochemical analysis was performed in undecalcified ...
متن کاملUrine calcium excretion predicts bone loss in idiopathic hypercalciuria.
Although idiopathic hypercalciuria (IH) is associated with reduced bone mineral density (BMD), no studies to date have identified predictors of BMD change over an extended period of observation. We have studied change in femoral neck and spine BMD z-scores in men and women with IH and stone disease (IHSF) and their first-degree relatives in order to determine the predictive value of commonly ma...
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ژورنال
عنوان ژورنال: World Journal of Nephrology
سال: 2012
ISSN: 2220-6124
DOI: 10.5527/wjn.v1.i2.54