Bone Density around Titanium Dental Implants Coating Tested/Coated with Chitosan or Melatonin: An Evaluation via Microtomography in Jaws of Beagle Dogs

Peri-implant bone density plays an important role in the osseointegration of dental implants. The aim study was to evaluate via micro-CT, Hounsfield units, around implants coated with chitosan and melatonin compare it a conventional etched surface after 12 weeks immediate post-extraction placement jaws Beagle dogs. Six dogs were used, 48 randomly placed: three groups—melatonin, chitosan, control. Seven 10 mm × regions interest defined each implant (2 crestal zone, 4 medial 1 apical zone). A total 336 sites studied AMIDE tool, using Norton Gamble classification assess density. effect on coating variables (chitosan, melatonin, control) at crestal, medial, positions (P2, P3, P4, M1) analyzed bivariate multivariate levels (linear regression). Adjusted effects did not indicate statistical significance for coatings (p = 0.653) but different ROIs < 0.001) 0.032). Micro-CT, appropriate software, proved be powerful tool measuring osseointegration.