BNP, TnI and Lactic Acid variations in Warm Blood Cardioplegia vs Cold Crystalloid Cardioplegia in Coronary Artery Bypass Grafting (CABG)

Introduction: Myocardial protection is one of the key points during cardiac surgery. Inadequate myocardial in cross-clamping period an issue concern Cardioplegic solutions improve tolerance ischemia and reperfusion by preserving energy reserves, preventing osmotic, electrolyte imbalances acidosis. Warm blood cardioplegia (WBC) has had a profound impact, especially coronary artery bypass surgery there have been many studies that compared it with Cold crystalloid (CCC). A good will be reflected on patients outcome, postoperative ICU strategy, morbidity mortality as well. Brain Natriuretic Peptide (BNP), Troponin I (TnI) Lactic Acid LA) are very significant biomarkers reflects adequate organ perfusion/protection. The purpose this study to determine if warm offers any advantages comparison CCC Coronary Artery Bypass Grafting (CABG) based primary variations BNP, TnI Acid. Patients method: 60 disease (CAD) Surgery (CABG), were retrospectively randomized two groups 30 different techniques protection: group CCC, B (WBC), according Calafiore [1] protocols). Intraoperative variables used assess outcomes. Results: This found benefits clinical outcome after CABG Keywords :Myocardial protection, Cardiac surgery, Cardiopulmonary Bypass, Calafiore, Cardioplegia, DOI: 10.7176/ALST/95-02 Publication date: November th 2022