BMP9 expression in the adult rat brain

Bone morphogenetic protein 9 (BMP9), also known as growth differentiation factor 2 (GDF2), is a member of the transforming ? (TGF ?) superfamily. Although BMP9 plays pivotal roles during development, including angiogenesis, hematopoiesis, hepatogenesis, osteogenesis, and glucose metabolism, little information available for expression in central nervous system (CNS). We, thus, investigated adult rat CNS using immunohistochemistry. was intensely expressed most neurons their axons. Furthermore, we found that oligodendrocytes ependymal cells express protein. These data indicate widely throughout CNS, this abundant strongly supports idea important brain.