Blood Pressure Lowering and Vasomodulator Effects of Piperine

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Blood pressure lowering and vasomodulator effects of piperine.

This study was aimed to explore underlying mechanism(s) of cardiovascular effects of piperine. Intravenous administration of piperine caused a dose-dependent (1 to 10 mg/kg) decrease in mean arterial pressure (MAP) in normotensive anesthetized rats; the next higher dose (30 mg/kg) did not cause any further change in MAP. The fall in blood pressure (BP) was followed by small increase in MAP afte...

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ژورنال

عنوان ژورنال: Journal of Cardiovascular Pharmacology

سال: 2008

ISSN: 0160-2446

DOI: 10.1097/fjc.0b013e31818d07c0