Blood-Derived Extracellular RNA and Platelet Pathobiology
نویسندگان
چکیده
منابع مشابه
Blood-Derived Extracellular RNA and Platelet Pathobiology
The interaction between blood cells and disease has continued to grow both more complex and increasingly intriguing. Once thought to be static populations, circulating blood cells are now known to interact and communicate in ways far beyond the singular processes historically attributed to each population. A primary example is the platelet, an anucleate cell with a traditional role in hemostasi...
متن کاملBlood-Derived Extracellular RNA and Platelet Pathobiology
The interaction between blood cells and disease has continued to grow both more complex and increasingly intriguing. Once thought to be static populations, circulating blood cells are now known to interact and communicate in ways far beyond the singular processes historically attributed to each population. A primary example is the platelet, an anucleate cell with a traditional role in hemostasi...
متن کاملBlood-Derived Extracellular RNA and Platelet Pathobiology
The interaction between blood cells and disease has continued to grow both more complex and increasingly intriguing. Once thought to be static populations, circulating blood cells are now known to interact and communicate in ways far beyond the singular processes historically attributed to each population. A primary example is the platelet, an anucleate cell with a traditional role in hemostasi...
متن کاملAn Overview on Platelet-derived Microparticles in Platelet Concentrates: blood collection, method preparation and storage
Preparations of platelet concentrates (PCs) that are stored under blood bank conditions and used for transfusion purposes, appear to be enriched in platelet derived-microparticles (PMPs) with high coagulant activity that may change platelet efficacy and safety issues. High shear stress could cause shedding of PMPs from the platelet plasma membrane, platelet aggregation, and activation of the co...
متن کاملIsolation and characterization of platelet-derived extracellular vesicles
BACKGROUND Platelet-derived extracellular vesicles (EVs) participate, for example, in haemostasis, immunity and development. Most studies of platelet EVs have targeted microparticles, whereas exosomes and EV characterization under various conditions have been less analyzed. Studies have been hampered by the difficulty in obtaining EVs free from contaminating cells and platelet remnants. Therefo...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2016
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.115.308190