BLOOD COAGULATION INITIATION BY A COMPLEMENT-MEDIATED PATHWAY
نویسندگان
چکیده
منابع مشابه
Blood Coagulation Initiation by a Complement-mediated Pathway
A variety of complement-activating substances, including inulin, immunoglobulin aggregates, bacterial endotoxins, and staphylococcal protein A, were found to initiate blood coagulation through a complement-mediated pathway. These substances markedly accelerated blood coagulation in normal rabbit blood. That this clot-promoting activity requires an intact complement system was demonstrated by an...
متن کاملBlood Coagulation Initiation
Bacterial endotoxins and antigen-antibody aggregates activate complement, accelerate blood coagulation, and are implicated in intravascular blood clotting (1-7). Tha t their effect on blood coagulation proceeds through the activation of the complement system has been suspected bu t has never been shown. We have found that these and other complement-activating materials initiate blood coagulatio...
متن کاملMicroparticles and a P-Selectin-Mediated Pathway of Blood Coagulation
Alessandro Celia,c, Roberto Lorenzetb, Barbara C. Furiec and Bruce Furiec,∗ Laboratorio di Biologia Cellulare Respiratoria, Dipartimento Cardiotoracico dell’Universit à di Pisa, Pisa, Italy Antonio Taticchi Unit for Atherosclerosis and Thrombosis, Istituto Ricerche Farmacologiche Mario Negri, Consorzio Mario Negri Sud, S. Maria Imbaro, Italy Center for Hemostasis and Thrombosis Research, Beth I...
متن کاملmannose-binding lectin mediated complement pathway in autoimmune neurological disorders
multiple sclerosis (ms) is a complex, demyelinating disease of the central nervous system (cns) with variable phenotypic presentations, while guillain-barre syndrome (gbs) is the prototypic acute inflammatory disorder that affects the peripheral nervous system. myasthenia gravis (mg) is a t cell dependent and antibody mediated autoimmune disease. although it has been shown that complement plays...
متن کاملInitiation of the blood coagulation mechanisms.
IN the physiology of hemostasis the coagulation of the blood is one of the dominant events. When the complicated chemical interactions fail, persistent bleeding and even a fatal outcome may be expected. Since blood may remain fluid in the blood vessels for a lifetime, but nevertheless clot in a few minutes when shed, it is consequential to ask what initiates the complicated chemical interaction...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1971
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.134.6.1601