Blockade of TIM3 relieves immunosuppression through reducing regulatory T cells in head and neck cancer
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چکیده
منابع مشابه
Blockade of TIM3 relieves immunosuppression through reducing regulatory T cells in head and neck cancer
BACKGROUND T-cell immunoglobulin mucin 3 (TIM3) is a negative immune checkpoint and plays a crucial part in tumor-induced immune suppression. However, the mechanism of TIM3 in regulating immunosuppression in head and neck squamous cell carcinoma (HNSCC) was still not quite clear. METHODS We carried out the immunohistochemistry staining of HNSCC tissue microarrays. Through quantification of th...
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ژورنال
عنوان ژورنال: Journal of Experimental & Clinical Cancer Research
سال: 2018
ISSN: 1756-9966
DOI: 10.1186/s13046-018-0713-7