Blepharospasm, dry eye and extractable nuclear antigen antibodies

Dry eye, blinking, and blepharospasm.

The primary purpose of the eyelids is to ensure corneal integrity. An important component of this protective function is maintaining the corneal tear film. Blink characteristics can determine tear film stability. Increasing blink amplitude thickens the lipid layer that overlies the aqueous layer of the tear film. This thickening reduces evaporation of the aqueous layer. Because each blink refor...

Detection of antibodies to double stranded DNA and extractable nuclear antigen.

Botulinum toxin A treatment in patients suffering from blepharospasm and dry eye.

BACKGROUND Many patients with essential blepharospasm also show dry eye signs and symptoms. Botulinum toxin A is an effective treatment for reducing spasms in these patients. In this investigation, the effect of botulinum toxin A injections on tear function and on the morphology of the ocular surface in patients suffering from blepharospasm in combination with a dry eye syndrome was investigate...

349 Detection of Anti-nucclear Antibodies (ana) Used for Diagnostic Approach of Systemic Autoimmune Diseases. Correlation with Double Stranded DNA (DSDNA) and Extractable Nuclear Antigen (ENA) Antibodies

revealed that the levels of IgG-abs to HSV were being increased in proportion to a severity of AD. Maximal increased level of IgG-abs to HSV was in children with severe AD (Me 1⁄4 2.93 units of OD (0.14–3.15); P , 0.05). Conclusions: The detection of the elevated levels of the autoantibodies, especially against the background of herpetic infection, amplifies the phenotypic and diagnostic criter...

Extractable nuclear antigen effect on the DNA anti-DNA reaction and NZB/NZW mouse nephritis.

Extractable nuclear antigen (ENA) is composed of at least two components, one a ribonucleo-protein sensitive to ribonuclease or heat and the other a protein. Antibodies to ENA are associated with a relatively benign clinical course in patients with systemic lupus erythematosus (SLE) in which DNA anti DNA complexes are thought pathogenic. The effect of ENA and anti-ENA on DNA anti-DNA reactions ...