bla KPC gene Detection in Clinical Isolates of Carbapenem Resistant Enterobacteriaceae in a Tertiary Care Hospital

blaKPC gene Detection in Clinical Isolates of Carbapenem Resistant Enterobacteriaceae in a Tertiary Care Hospital.

INTRODUCTION Carbapenem resistance among Enterobacteriaceae, especially in Klebsiella pneumoniae and Escherichia coli, is an emerging problem worldwide. A common mechanism of carbapenem resistance is the production of class-A, Klebsiella pneumoniae carbapenemase (KPC). AIMS AND OBJECTIVES The present study focused on determining the antibiotic resistance pattern and prevalence of bla KPC gene...

Detection of Carbapenem Resistant Gram-Negative Bacteria in Clinical Isolates from a Tertiary Care Hospital

Multidrug-resistant Gram-negative bacteria are a major public health threat. However, intense efforts to limit their spread, the number of multidrug resistant Gram-negative bacteria continues to increase globally. Carbapenems, the most broad-spectrum beta lactam antibiotics active against Gram-negative organisms, are very slowly hydrolyzed by most beta-lactamases. Because of their broad-spectru...

Prevalence of bla-NDM gene in the carbapenem drug resistant Klebsiella spp isolated from the tertiary care centre

Introduction and objectives: Antimicrobial resistant (AMR) is a serious global threat and World Health Organization (WHO) declared AMR is the one among 10 public health threat facing the humanity. Increase in Carbapenem resistant is the major problem which hinders the patient treatment. Various genes are responsible for carbapenem resistant but the gene bla-NDM has the ability to inactivate var...

Characterization of carbapenem-resistant Acinetobacter baumannii clinical isolates in a tertiary care hospital in Saudi Arabia.

This study characterized the occurrence of carbapenem resistance of Acinetobacter baumannii isolates in a tertiary care hospital in Saudi Arabia. From January 2010 until February 2012, Acinetobacter spp. isolates were collected from different wards and were identified using Vitek 2 system and 16S rRNA gene sequencing. Vitek 2 system and Etest were used for susceptibility testing. PCR and Pulse ...

Detection of bla(GES-5) in carbapenem-resistant Kluyvera intermedia isolates recovered from the hospital environment.