Bisphosphonates for Postmenopausal Osteoporosis

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منابع مشابه

intravenous bisphosphonates for postmenopausal osteoporosis

abstract numerous clinical studies have shown bisphoshonates (bps) to be useful and cost-effective options for the fractures prevention and postmenopausal bone loss. the use of oral bisphoshonates is an established option for managment of osteoporosis in postmenopausal women, but many of them complaint from gastrointestinal side effect or frequently dosed oral regimens. to improve upon the subo...

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The leading treatments for postmenopausal osteoporosis are the nitrogen-containing bisphosphonates, which are required long term for optimal benefit. Oral bisphosphonates have proven efficacy in postmenopausal osteoporosis in clinical trials, but in practice the therapeutic benefits are often compromised by patients' low adherence. Nonadherence to bisphosphonate therapy negatively impacts outco...

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Bisphosphonates for osteoporosis.

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Update on long-term treatment with bisphosphonates for postmenopausal osteoporosis: a systematic review.

INTRODUCTION Osteoporosis is a progressive skeletal disorder that requires long-term treatment. However, there is little guidance regarding optimal treatment duration and what the treatment discontinuation and retreatment criteria should be. Given that bisphosphonates are the most commonly prescribed class of agent for the treatment of osteoporosis, we reviewed the long-term data relating to th...

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Antiresorptive Drugs Beyond Bisphosphonates and Selective Oestrogen Receptor Modulators for the Management of Postmenopausal Osteoporosis

Osteoporotic fractures are a major cause of morbidity in the elderly population. Since postmenopausal osteoporosis is related to an increase in osteoclastic activity at the time of menopause, inhibitors of bone resorption have genuinely been considered an adequate strategy for prevention and treatment of osteoporosis. Bisphosphonates and selective oestrogen receptor modulators are widely prescr...

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ژورنال

عنوان ژورنال: JAMA

سال: 2021

ISSN: 0098-7484

DOI: 10.1001/jama.2020.2923