Birthing of a daughter vesicle in a model system for self-reproduction vesicles

Sakuma and Imai [Phys. Rev. Lett. 107, 198101 (2011)] established a temperature-controlled cyclic process for model system of self-reproducing vesicles without feeding. The vesicle generates smaller inclusion called "daughter vesicle" inside the original (we call this "mother vesicle") then daughter is expelled through small pore on mother vesicle. This birthing. In present study we theoretical birthing single, rigid pore. By using simple geometric picture, derive free energy constituting material properties bending, stretching line tension moduli vesicle, as function distance between centers vesicles, size We see clearly disappearance barrier by selecting appropriate moduli. dynamics studied employing Onsager principle. results indicate that translocation time decreases friction parameter decreases, or initial decreases.