Biphasic calcium phosphate–casein bone graft fortified with Cassia occidentalis for bone tissue engineering and regeneration
نویسندگان
چکیده
منابع مشابه
Biphasic Calcium Phosphate Ceramics for Bone Regeneration and Tissue Engineering Applications
Biphasic calcium phosphates (BCP) have been sought after as biomaterials for the reconstruction of bone defects in maxillofacial, dental and orthopaedic applications. They have demonstrated proven biocompatibility, osteoconductivity, safety and predictability in in vitro, in vivo and clinical models. More recently, in vitro and in vivo studies have shown that BCP can be osteoinductive. In the f...
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Introduction: Bone is one of the tissues that have a true potential for regeneration. However, sometimes the bone defects are so outsized that there is no chance of bone self-repair and restoration or the damage is such that it is not possible to repair with medical or surgical interventions. In these situations, bone grafts are the treatment of choice, but due to several obstacles, including l...
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Biological mechanism of bone repair mainly involves both osteoconductivity and osteoinductivity. Scaffolds with osteoinductivity can give biological signals to stimulate the proliferation and differentiation of bone marrow mesenchymal stem cells and osteoblast-like cells to promote bone regeneration. Although most scaffolds for bone tissue engineering demonstrate osteoconductivity, they lack os...
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1 Department of Surgery, University of Michigan Health Systems, Taubman Center, 1500 East Medical Center Drive, XPC 5340, Ann Arbor, MI 48109-0219, USA 2Orthopedic Hospital Research Center, David Geffen School of Medicine, University of California, Los Angeles, 615 Charles E. Young Drive South, Room 410, Los Angeles, CA 90095, USA 3 Center for Cardiovascular Science and MRC Center for Regenerat...
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Aligned and random nanocomposite nanofibrous scaffolds were electrospun from polycaprolactone (PCL), poly (vinyl alcohol) (PVA) and hydroxyapatite nanoparticles (nHA). The morphology and mechanical characteristics of the nanofibers were evaluated using scanning electron microscopy and tensile testing, respectively. Scanning electron microscopy revealed fibers with an average diameter of 123 ± 3...
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ژورنال
عنوان ژورنال: Bulletin of Materials Science
سال: 2015
ISSN: 0250-4707,0973-7669
DOI: 10.1007/s12034-014-0799-2