Biotechnological applications of mammalian odorant-binding proteins
نویسندگان
چکیده
The olfactory system of mammals allows the detection and discrimination thousands odors from environment. In mammals, odorant-binding proteins (OBPs) are considered responsible to carry odorant molecules across aqueous nasal mucus receptors (ORs). three-dimensional structure these presents eight antiparallel ?-sheets a short ?-helical segment close C terminus, typical lipocalins family. great ability OBPs bind differentiated ligand has driven research understand mechanisms underlying OBP function in nature development advanced biotechnological applications. This review describes role mammalian perception, highlighting influence several key parameters (amino acids, temperature, ionic strength, pH) formation OBP/ligand complex. information literature regarding structure, affinity, strength binding, stability inspiring applications herein detailed.
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ژورنال
عنوان ژورنال: Critical Reviews in Biotechnology
سال: 2021
ISSN: ['1549-7801', '0738-8551']
DOI: https://doi.org/10.1080/07388551.2020.1853672