Biosynthesis of Salbutamol-4′-O-sulfate as Reference for Identification of Intake Routes and Enantiopure Salbutamol Administration by Achiral UHPLC-MS/MS

solid lipid microparticles of salbutamol sulfate for dry powder inhalation

Unsuspected coronary artery disease revealed by administration of nebulised salbutamol.

native-valve-endocarditis-using transesophageal echocardiography: implications for surgical treatment. Thorac Cardiovasc Surg 1991;39:273-80. 15 John RM, Pugsley W, Treasure T, Sturridge MF, Swanton RH. Aortic root complications of infective endocarditis-influence on surgical outcome. Eur Heart J 1991; 12:241-8. 16 Wong CM, Oldershaw P, Gibson DG. Echocardiographic demonstration of aortic root ...

An aerosol formulation of R-salbutamol sulfate for pulmonary inhalation.

An aerosol formulation containing 7.5 mg of R-salbutamol sulfate was developed. The aerosol was nebulized with an air-jet nebulizer, and further assessed according to the new European Medicines Agency (EMA) guidelines. A breath simulator was used for studies of delivery rate and total amount of the active ingredient at volume of 3 mL. A next generation impactor (NGI) with a cooler was used for ...

Aerosol salbutamol administration by IPPB: lowest effective dose.

This study was conducted to determine whether small doses of salbutamol solution, aerosolised and delivered by intermittent positive-pressure breathing (IPPB), would be as effective as the 5 to 10 mg dose usually recommended for inhalational use. In nine asthmatic subjects we found that there was no significant difference between the peak bronchodilator effect of 1.0, 2.5, and 5.0 mg of salbuta...

Bioavailability assessment of salbutamol sulfate suppositories in human volunteers.

The purpose of this investigation was to evaluate the bioavailability of three salbutamol sulfate suppository formulations. The formulations were; 2 mg salbutamol sulfate in Suppocire NA base containing 6% Eudispert gel (F1), 2mg salbutamol sulfate in Witepsol H15 base containing 3% methyl cellulose gel (F2), and 2 mg salbutamol sulfate in Witepsol W25 base containing 3% methyl cellulose gel (F...