Biosynthesis of L-lysine and L-threonine in Brevibacterium. Part IX. Production of L-lysine by fluoropyruvate-sensitive mutants of Brevibacterium lactofermentum.
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چکیده
منابع مشابه
Microbial Production of L-lysine I. Production by Auxotropiis of Brevibacterium Elavum
Seven homoserine, 42 methionine, 42 threonine, and 15 isoleucine auxotrophs were obtained from Brevibacterium flavum No. 2247 (ATCC No. 14067) by X-ray irradiation and N-methyl-N'-nitro-N-nitrosoguanidine treatment. Concerning the L-lysine-producing ability, the homoserine auxotrophs were the best and about one-half of the threonine auxotrophs ranked next. The rest of threonine auxotrophs and a...
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A novel type of threonine-producing strains, dihydrodipicolinate synthase (DPS)-defective mutants of Brevibacterium flavum, was isolated as alpha-amino-beta-hydroxyvaleric acid (AHV)-resistant producers. The third selection markers used were a strong lysine inhibition of threonine production and a lower production of lysine than that of threonine in those derived from strains with feedback-sens...
متن کاملCloning and characterization of genes responsible for m-fluoro-D,L-phenylalanine resistance in Brevibacterium lactofermentum.
Two kinds of 3-deoxy-D-arabino-hepturosonate-7-phosphate (DAHP) synthase genes were cloned from an L-Phe-producing mutant of Brevibacterium lactofermentum, AJ11957, which was resistant to m-fluoro-D,L-phenylalanine (mFP) and p-fluoro-D,L-phenylalanine (pFP) and which had DAHP synthase free from feedback inhibition. Both genes were cloned using a vector plasmid, pAJ1844, and the resulting recomb...
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5-Aminovalerate is a potential C5 platform chemical for synthesis of valerolactam, 5-hydroxyvalerate, glutarate, and 1,5-pentanediol. It is a metabolite of l-lysine catabolism through the aminovalerate pathway in Pseudomonas putida. L-Lysine monooxygenase (DavB) and 5-aminovaleramide amidohydrolase (DavA) play key roles in the biotransformation of L-lysine into 5-aminovalerate. Here, DavB and D...
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اسید آمینه ال - لیزین یکی از اسیدهای آمینه ضروری برای دام و طیور می باشد، لذا در تغذیه آنها به عنوان یک مکمل غذایی از اهمیت ویژه ای برخوردار است . امروزه متداولترین منایع تولید لیزین، میکروارگانیسمها و خصوصا باکتریهای دو گونه بروی باکتریوم و کورینه باکتریوم می باشند. به منظور افزایش تولید این اسید آمینه در باکتریهای فوق، از ایجاد جهش و گرینش در سویه های مناسب استفاده می شود. سویه هایی که بدین ت...
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ژورنال
عنوان ژورنال: Agricultural and Biological Chemistry
سال: 1985
ISSN: 0002-1369,1881-1280
DOI: 10.1271/bbb1961.49.1305