Bioreactor Design for Tendon/Ligament Engineering
نویسندگان
چکیده
منابع مشابه
Special Issue: Design of Bioreactor Systems for Tissue Engineering
Tissue engineering and, more broadly, regenerative medicine is moving into a phase where we are seeing potential therapies moving 'slowly but surely' from the laboratory into the clinic, i.e., from research to the clinic and into manufacturing. The numbers of cells required for cell therapy protocols can vary from tens of millions, to billions [1], and it is widely considered that such cell num...
متن کاملDesign of a biaxial mechanical loading bioreactor for tissue engineering.
We designed a loading device that is capable of applying uniaxial or biaxial mechanical strain to a tissue engineered biocomposites fabricated for transplantation. While the device primarily functions as a bioreactor that mimics the native mechanical strains, it is also outfitted with a load cell for providing force feedback or mechanical testing of the constructs. The device subjects engineere...
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the aim of the present study was to develop a tissue-engineering approach through alginate gel molding to mimic cartilage tissue in a three-dimensional culture system. the perfusion biomimetic bioreactor was designed to mimic natural joint. the shear stresses exerting on the bioreactor chamber were calculated by computational fluid dynamic (cfd). several alginate/bovine chondrocyte constructs w...
متن کاملTissue Engineering Bioreactor
pg. 2) Background (pg. 2-8) Alternative Design Descriptions (pg. 8-11) Final Design (pg. 11-13) References (pg. 13) Appendix A: Product Design Specifications (pg. 13-16)
متن کاملBioreactor Systems for Human Bone Tissue Engineering
Critical size skeletal defects resulting from trauma and pathological disorders still remain a major clinical problem worldwide. Bone engineering aims at generating unlimited amounts of viable tissue substitutes by interfacing osteocompetent cells of different origin and developmental stage with compliant biomaterial scaffolds, and culture the cell/scaffold constructs under proper culture condi...
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ژورنال
عنوان ژورنال: Tissue Engineering Part B: Reviews
سال: 2013
ISSN: 1937-3368,1937-3376
DOI: 10.1089/ten.teb.2012.0295