منابع مشابه
Nanomechanics of HaloTag tethers.
The active site of the Haloalkane Dehydrogenase (HaloTag) enzyme can be covalently attached to a chloroalkane ligand providing a mechanically strong tether, resistant to large pulling forces. Here we demonstrate the covalent tethering of protein L and I27 polyproteins between an atomic force microscopy (AFM) cantilever and a glass surface using HaloTag anchoring at one end and thiol chemistry a...
متن کاملTelomeres, tethers and trypanosomes
Temporal and spatial organization of the nucleus is critical for the control of transcription, mRNA processing and the assembly of ribosomes. This includes the occupancy of specific territories by mammalian chromosomes, the presence of subnuclear compartments such as the nucleolus and Cajal bodies and the division of chromatin between active and inactive states. These latter are commonly associ...
متن کاملDirect Observation of Membrane Tethers Formed during Neutrophil Attachment to Platelets or P-Selectin under Physiological Flow
Adhesion and subsequent aggregation between neutrophils and platelets is dependent upon the initial binding of P-selectin on activated platelets to P-selectin glycoprotein ligand 1 (PSGL-1) on the microvilli of neutrophils. High speed, high resolution videomicroscopy of flowing neutrophils interacting with spread platelets demonstrated that thin membrane tethers were pulled from neutrophils in ...
متن کاملShort Tethers for Eiectrodynaraic Thrust
Abstract. The operational advantages of electrodynamic tethers of moderate length are becoming evident from studies of collision avoidance. Although long tethers (of order of 10 kilometers) provide high efficiency and good adaptability to varying plasma conditions, boosting tethers of moderate length (~ 1 kilometer) and suitable design might still operate at acceptable efficiencies and adequate...
متن کاملMembrane transport: Tethers and TRAPPs
Transport vesicles are tethered to their target membrane prior to the interaction of v-SNAREs and t-SNAREs across the membrane junction. Recent evidence suggests tethering is a complex process requiring multiple components.
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ژورنال
عنوان ژورنال: Life
سال: 2021
ISSN: 2075-1729
DOI: 10.3390/life11060515