Biomarkers of Oxidative Stress in Major Depressive Disorder
نویسندگان
چکیده
منابع مشابه
Mitochondrial dysfunction, oxidative stress, and major depressive disorder
There is controversy about depression being a physical illness, in part because a reproducible, sensitive, and specific biologic marker is not available. However, there is evidence that mitochondrial dysfunction and oxidative stress may be associated with abnormal brain function and mood disorders, such as depression. This paper reviews selected human and animal studies providing evidence that ...
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INTRODUCTION There is increasing evidence that oxidative stress plays an important pathophysiological role in severe psychiatric disorders. Glutathione (GSH) is a major intracellular antioxidant and redox regulator that protects cells against oxidative stress. Dysregulation of the GSH system has been hypothesized to reduce glutamatergic activity at the NMDA receptor and attenuate neurotrophin p...
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ژورنال
عنوان ژورنال: Open Access Macedonian Journal of Medical Sciences
سال: 2020
ISSN: 1857-9655
DOI: 10.3889/oamjms.2020.4144