Biomarkers of Obesity and Subsequent Cardiovascular Events
نویسندگان
چکیده
منابع مشابه
Biomarkers of obesity and subsequent cardiovascular events.
Obesity is a major risk factor for cardiovascular diseases, but the mechanisms for increased cardiovascular risk in obesity are still unclear. Inflammation and increased oxidative stress are two potential mechanisms proposed to play a major role in the morbidity associated with obesity. Studies that investigate these mechanisms rely on biomarkers, but validated biomarkers for obesity-related ca...
متن کاملBiomarkers, Obesity, and Cardiovascular Diseases
Obesity and overweight are among the major health problems in the world today. The excessive accumulation of fat in adipose tissue is accompanied by low‐grade inflamma‐ tion, adipokine secretion dysregulation, oxidative stress, and an alteration of the secretion of gut hormones and food intake related to peptides. This is related to the development of cardiovascular diseases, which have been in...
متن کاملBiomarkers for prediction of cardiovascular events.
To the Editor: Wang et al. (Dec. 21 issue)1 suggest that novel biomarkers in aggregate have little influence on the prediction of first cardiovascular events or death. We wonder whether there were sufficient analyses to warrant this conclusion. As described, there were only 68 “major” cardiovascular events in women and 101 in men. In the crucial multimarker analyses, a quarter of these events w...
متن کاملUse of Obesity Biomarkers in Cardiovascular Epidemiology
Obesity is an established risk factor for cardiovascular disease (CVD), yet, the underlying mechanisms are only poorly understood. The adipose tissue produces a variety of hormones and cytokines and thereby actively participates in a network of biomarkers that may be relevant for the development of CVD. Such obesity biomarkers have a great potential to better characterize the obesity phenotype ...
متن کاملObesity, risk factors, and predicting cardiovascular events.
APubMed search in March 2005 with the key word “metabolic syndrome” yielded 10 000 references. Past labels for this disorder include “syndrome X,” “deadly quartet,” and “cardiovascular dysmetabolic syndrome.”1–3 What is driving the current increased interest in the metabolic syndrome? Possibly the impetus comes from the dramatic increases in obesity in the United States and other developed coun...
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ژورنال
عنوان ژورنال: Epidemiologic Reviews
سال: 2007
ISSN: 0193-936X,1478-6729
DOI: 10.1093/epirev/mxm005