Biomarkers in Anderson–Fabry Disease

Biomarkers in Alzheimer’s Disease

Alzheimer's disease (AD) is the most common form of dementia in the elderly, and it is characterized by progressive impairment in multiple cognitive domains of sufficient severity to interfere with individuals' daily living activities. Historically, the diagnosis of AD has been based on the identification of a clinical syndrome, and accuracy studies of the current clinical criteria conducted in...

Biomarkers in Periodontal Disease

The current clinical diagnostic criteria were introduced almost a half century ago continue to use as the basic of oral diagnosis in today’s clinical practice. But the disadvantages are they measure disease severity rather than disease activity. Evolvement with time is brought us to the era of biomarkers. Biomarkers are micro molecules that can be used as to measure health status, disease onset...

Biomarkers in Acute Cardiac Disease

The use of biomarkers to aid diagnosis and treatment is increasing rapidly as genomics and proteomics help us expand the number of markers we can use and as an improved understanding of the pathophysiology of cardiac disease guides their use. However, as with all rapidly expanding fields, there is the risk of excessive enthusiasm unless we are circumspect about the data that guide the clinical ...

MRI biomarkers in Huntington's disease.

Huntington's disease (HD) is a devastating neurodegenerative disease affecting the brain resulting in neuronal dysfunction and neuronal loss. Since the identification of the gene responsible for HD, genetic testing has become widely available, allowing for genetic status of persons at risk for HD to be determined. For the effective evaluation of future therapeutic trials a great need exists for...

New Biomarkers in Autoimmune Disease