Biomarkers for noninvasive biochemical diagnosis of nonalcoholic steatohepatitis: Tools or decorations?
نویسندگان
چکیده
منابع مشابه
Biochemical Scoring System for diagnosing Nonalcoholic Steatohepatitis
Noor-E-Alam M, Alam S, Alam AKMK, Al Mahtab M, Rahman S. Biochemical Scoring System for diagnosing Nonalcoholic Steatohepatitis. Euroasian J Hepato-Gastroenterol 2016;6(2):202-204.
متن کاملNoninvasive evaluation of nonalcoholic steatohepatitis (NASH).
Sir Non-alcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of conditions, ranging from a simple fatty liver to non-alcoholic steatohepatitis (NASH) with or without fibrosis, to cirrhosis and its complications (1). It is important to distinguish NASH from simple fatty liver because NASH patients are in greater risk of developing cirrhosis, liver failure and hepatocellular carcinom...
متن کاملCytokeratin-18 fragment levels as noninvasive biomarkers for nonalcoholic steatohepatitis: a multicenter validation study.
UNLABELLED Liver biopsy remains the gold standard for diagnosing nonalcoholic steatohepatitis (NASH). We have recently demonstrated that plasma cytokeratin 18 (CK-18) fragment levels correlate with the magnitude of hepatocyte apoptosis and independently predict the presence of NASH. The goal of this study was to validate the use of this biomarker for NASH diagnosis. The study was an ancillary s...
متن کاملApoptosis and diagnosis of nonalcoholic steatohepatitis
Abbreviations: NAFLD, nonalcoholic fatty liver disease; NASH, nonalcoholic steatohepatitis; NAS, NAFLD activity score; ALT, alanine aminotransferase; GGT, γ-glutamyl transpeptidase; BMI, body mass index; AST, aspartate aminotransferase; CK-18, cytokeratin 18; sFas, soluble Fas; AUC, area under curve Corresponding author: Chang Wook Kim Department of Internal Medicine, Uijeongbu St. Mary’s Hospi...
متن کاملA novel pathophysiological-based panel of biomarkers for the diagnosis of nonalcoholic steatohepatitis.
Non-invasive biochemical markers are useful to distinguish between nonalcoholic steatohepatitis (NASH) and simple steatosis. The aim of this study was to test the diagnostic value of a panel of biomarkers derived from the pathophysiological events involved in the development of NASH. A total of 79 patients: 20 not-NASH and 59 NASH were included in the study. Definitive NASH was defined accordin...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2009
ISSN: 1007-9327
DOI: 10.3748/wjg.15.4346