BIOLOGICAL STUDIES WITH 4-AMINO-10-METHYLPTEROYLGLUTAMIC ACID
نویسندگان
چکیده
منابع مشابه
Acoustical Studies of Some Derivatives of 4-Amino Benzoic Acid in 1, 4-Dioxane and Dimethyl Formamide at 308.15 K
The ultrasonic velocity, density and viscosity of some Schiff bases of 4-amino benzoic acid were measured in 1,4-dioxane and dimethylformamide at 308.15 K. Various acoustical properties such as isentropic compressibility (ks), Rao’s molar sound function (Rm), the Van der Waals constant (b), molar compressibility (W), inter molecular free len...
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that folic acid antagonists provide temporary palliation in certain cases of acute leukemia in children (7) and that several compounds of this class increase the survival time of mice with transplanted leukemia Ak 4 (4, 10, 11). However, eventual failure in the treatment of leukemia by chemotherapy with such compounds occurs consistently. The mechanism involved in the development of drug resist...
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The title compounds 6aâj, 2-[(6-methyl-1,3-benzothiazol-2-yl)amino]-N-[2-(substituted phenyl/furan-2-yl)-4-oxo-1,3-thiazolidin-3-yl]nicotinamides, were prepared from 2-chloropyridine-3-carboxylic acid (1) and 2-amino-6-methyl-benzothiazole (2) by known methods. All the compounds have been established by IR, (1)H NMR, (13)C NMR and elemental analyses. The in vitro antimicrobial screening of the ...
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In the title compound, C(14)H(10)FNO(2), the benzene rings make a dihedral angle of 57.50 (13)°, and the molecule has an E configuration about the C=N bond. In the crystal, molecules are linked via pairs of O-H⋯O hydrogen bonds, forming inversion dimers.
متن کامل4-[(2-Fluorophenyl)amino]-4-oxobutanoic acid
The crystal structure of the title compound, C(10)H(10)FNO(3), contains dimers of the asymmetric unit, with R(2) (2)(8) rings arising from inter-molecular O-H⋯O hydrogen bonding through the carboxyl-ate groups. Adjacent dimeric units are connected to each other through one N-H⋯O and two C-H⋯O inter-molecular hydrogen bonds. C-H⋯O hydrogen bonds involving the aromatic ring and the O atoms of two...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1949
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)57006-x