Biological and Pathological Characteristics of Thymic Epithelial Tumors
نویسندگان
چکیده
منابع مشابه
Treatment Results and Prognostic Indicators in Thymic Epithelial Tumors: A Clinicopathological Analysis of 45 Patients
Background: Thymomas are rare epithelial tumors arising from thymus gland. This study aims at investigating the clinical presentation, prognostic factors and treatment outcome of forty five patients with thymoma and thymic carcinoma. Methods: Forty-five patients being histologically diagnosed with thymoma or thymic carcinoma that were treated and followed-up at a tertiary academic hospital duri...
متن کاملRelationship Between CT Manifestations of Thymic Epithelial Tumors and the WHO Pathological Classification
Thymic epithelial tumors account for 15-21.7% of mediastinal tumors and 47% of anterior mediastinal tumors (Chen et al., 2002; Engels and Pfeiffer, 2003). Until 2004, there was a wide range of pathological classifications for thymic tumors (Travis et al., 2004; Okumura et al., 2008). The World Health Organization (WHO) updated the pathological classification in 2004, and thymic tumors are now c...
متن کاملExpression of RAGE and HMGB1 in Thymic Epithelial Tumors, Thymic Hyperplasia and Regular Thymic Morphology
Recently, a role of the receptor for advanced glycation endproducts (RAGE) in myasthenia gravis was described. RAGE and its ligand high mobility group box 1 (HMGB1) play key roles in autoimmunity and cancer. To test whether these molecules are involved in patients with thymic abnormalities we applied immunohistochemical analysis in 33 cases of thymic epithelial tumors, comprising 27 thymomas an...
متن کاملNovel Biologic Therapies for Thymic Epithelial Tumors
Thymic epithelial tumors (TETs) are comprised of a spectrum of histologically distinct tumors that also exhibit differences at the molecular level (1). Surgery is the mainstay of treatment but locally advanced and metastatic TETs can be inoperable and are associated with worse survival (2). Although multi-agent chemotherapy is associated with objective response rates (ORR) of 50–90% in the fron...
متن کاملMalignant thymic epithelial tumors: CT-pathologic correlation.
OBJECTIVE The purpose of our study was to describe and compare the CT and pathologic findings of atypical thymoma and thymic carcinoma. MATERIALS AND METHODS Twenty-seven consecutive patients (14 men, 13 women ranging in age from 22 to 77 years [mean age, 52 years]) with pathologically proven atypical thymoma (n = 9) and thymic carcinoma (n = 18) constituted the study population. The chest CT...
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ژورنال
عنوان ژورنال: The Journal of the Japanese Association for Chest Surgery
سال: 1990
ISSN: 0917-4141,1884-1724
DOI: 10.2995/jacsurg1987.4.6_627