Biological Activity of Thiamine Anhydride

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Oxidation Product of Thiamine Anhydride and the Metabolite of Thiamine Anhydride in Rats.

As shown in the previous paper, a metabolite of thiamine anhydride (TA) (I) was isolated as crystals melting at 172-173•‹ from the urine when TA was given parenterally to rats and it was assumed to be thiamine anhydride sulfoxide (TAO) (II) from its analytical data. It is known, however, that TA can be oxidized to TA sulfone (III) besides its sulfoxide by hydrogen peroxide according to the con ...

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ژورنال

عنوان ژورنال: YAKUGAKU ZASSHI

سال: 1957

ISSN: 0031-6903,1347-5231

DOI: 10.1248/yakushi1947.77.11_1230