Biological Activities of Lamiaceae Species: Bio-Guided Isolation of Active Metabolites from Salvia officinalis L.

Lamiaceae family includes various medicinal and aromatic plants used in cosmetics pharmaceutical industries. The present study aimed to investigate vitro the cytotoxic, photoprotective antioxidant activities of ten taxa; Melissa officinalis subsp. altissima (Sm.) Arcang., Rosmarinus L., Salvia Sideritis cypria Post, S. euboea Heldr., perfoliata L. perfoliata, scardica Griseb., sipylea Boiss., Stachys iva Thymus vulgaris aqueous extract was bio-guided fractionated obtain main bioactive metabolites, which were evaluated for aforementioned effects their wound-healing potential. In total, five compounds isolated identified through NMR spectra, namely salvianic acid A, rosmarinic acid, salvianolic K, luteolin-3′-O-β-D-glucuronide hispidulin-7-O-β-D-glucuronide. All non while no statistically significant oxidative stress reduction obtained. Regarding potential, K most promising candidate. Overall, this suggests natural agents from species, widely found Greece, provides a better insight into its constituents.