Biologic Treatment of Mild and Moderate Intervertebral Disc Degeneration
نویسندگان
چکیده
منابع مشابه
incidence of microscopic lumbar intervertebral disc calcification and its correlation to endplate degeneration type and disc histopathologic angiogensis
چکیده ندارد.
15 صفحه اول[Biological treatment for intervertebral disc degeneration].
Neck shoulder pain or lumbocrural pain caused by intervertebral disc degeneration (IDD) could seriously affect the qualities life of patients. Current treatments mainly focus on alleviating pain and the symptoms of nerve compression, which could not radically stop the process of intervertebral disc degeneration, but conversely lead to high recurrence rate. In recent years, scholars have turned ...
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Degenerative disc disease is a serious health problem worldwide, whose etiological basis – mechanical stimulus, biochemical changes, or natural aging – is poorly understood. While the disc’s known function is that of dynamic shock absorber, its dynamic response has not been fully characterized throughout the disc health spectrum (from healthy to degenerate). Therefore, this study aimed to corre...
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The intervertebral disc is a cartilaginous structure that resembles articular cartilage in its biochemistry, but morphologically it is clearly different. It shows degenerative and ageing changes earlier than does any other connective tissue in the body. It is believed to be important clinically because there is an association of disc degeneration with back pain. Current treatments are predomina...
متن کاملPotential biologic therapies for the intervertebral disc.
Biology offers several strategies for restoring the degenerating disc, including the use of recombinant or natural proteins that increase matrix accumulation and assembly, enhance the number of disc cells, or in other ways lead to restoration of the native healthy disc. Recombinant bone morphogenetic protein-7 (osteogenic protein-1) shows promise in this regard. Other growth factors, as well as...
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ژورنال
عنوان ژورنال: Molecular Medicine
سال: 2014
ISSN: 1076-1551,1528-3658
DOI: 10.2119/molmed.2014.00145