منابع مشابه
Biologic treatment in glomerular disease.
to the standard immunosuppressive treatment demonstrating its limitations and the current unmet need of, at least, similarly effective and less toxic treatment. To illustrate the close connection between a better understanding of the pathogenesis of the disease and targeted treatment, the papers on the pathogenesis of ANCA-associated vasculitis [2] , lupus nephritis [3] , the role of anti-PLA2R...
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Chronic kidney disease (CKD) is becoming a major public health issue worldwide, mainly due to the increasing prevalence of hypertension, diabetes and aging population. Chronic hepatitis C virus (HCV) infection commonly involves the kidneys, can be a cause of CKD, and significantly impacts morbidity and mortality in these patients. Prompt recognition and knowledge of how to best manage these pat...
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• Objective: To review the role of the biologic agents in therapy for Crohn’s disease, with particular emphasis on efficacy, indications for use, and impact on disease outcomes. • Methods: Qualitative review of the literature and
متن کاملMizoribine in the treatment of pediatric-onset glomerular disease.
BACKGROUND Mizoribine (MZR) is a selective inhibitor of inosine monophosphate dehydrogenase, a key enzyme in the pathway responsible for de novo synthesis of guanine nucleotides. As an immunosuppressant, MZR has been used successfully without any serious adverse effects in the treatment of renal diseases in children as well as adults. Besides its immunosuppressive effect, MZR has been reported ...
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GVA Gastroenterologists need to know that biologic agents have been under study for more than 15 years now, and a lot has been learned about their benefits and risks. The anti–tumor necrosis factor (TNF) agents are currently dominating the field of biologic therapy in inflammatory bowel disease (IBD). The armamentarium is relatively small for gastroenterologists compared with that for rheumatol...
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ژورنال
عنوان ژورنال: Nephron Clinical Practice
سال: 2014
ISSN: 1660-2110
DOI: 10.1159/000369646